Alkaloids of Anchusa officinalis L.. Identification of the Pyrrolizidine Alkaloid Lycopsamine.
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چکیده
منابع مشابه
ALKALOIDS OF BORAGINACEAE II [I], PYRROLIZIDINE, ALKALOIDS OF HELIOTROPIUM E UROPAEUM L. POPULATION GARMSAR
Helitropium europaeum L. population Garmsar was shown to contain three major alkaloids: heliotrine N-oxide (2), lasiocarpine (4) and lasiocarpine N-oxide (5); and four minor alkaloids: heliotrine (I), europine (3), acetyllasiocarpine (6) and a novel alkaloid acetyllasiocarpine N-oxide (7).
متن کاملIdentification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism.
Pyrrolizidine Alkaloids (PAs) are currently one of the most important botanical hepatotoxic ingredients. Glutathion (GSH) metabolism is the most reported pathway involved in hepatotoxicity mechanism of PAs. We speculate that, for different PAs, there should be a common mechanism underlying their hepatotoxicity in GSH metabolism. Computational methods were adopted to test our hypothesis in consi...
متن کاملPyrrolizidine Alkaloids from Heliotropium
Investigation of the pyrrolizidine alkaloids of Heliotropium arbainense resulted in the isolation and identification of heliotrine, europine and 7-angelylheliotrine. From H. ovalifolium three alkaloids were isolated: supinine, 7-angelylheliotridine and an alkaloid which was shown to be of the heliotridine monoester type with a dehydrated viridifloric acid.
متن کاملPyrrolizidine alkaloids in human diet.
Pyrrolizidine alkaloids are the leading plant toxins associated with disease in humans and animals. Upon ingestion, metabolic activation in liver converts the parent compounds into highly reactive electrophiles capable of reacting with cellular macromolecules forming adducts which may initiate acute or chronic toxicity. The pyrrolizidine alkaloids present a serious health risk to human populati...
متن کاملalkaloids of boraginaceae ii [i], pyrrolizidine, alkaloids of heliotropium e uropaeum l. population garmsar
helitropium europaeum l. population garmsar was shown to contain three major alkaloids: heliotrine n-oxide (2), lasiocarpine (4) and lasiocarpine n-oxide (5); and four minor alkaloids: heliotrine (i), europine (3), acetyllasiocarpine (6) and a novel alkaloid acetyllasiocarpine n-oxide (7).
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1980
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.34b-0075